Can I run gpt-oss-20b on a Radeon Pro W6400?
Not at these settings. No indexed quantization of gpt-oss-20b fits Radeon Pro W6400 at any context we compute, with q4_0 KV. The smallest shipped quantization is 10.68 GiB in weights alone, against 3.72 GiB usable. CPU offload can still run it, slowly.
Every quantization at every context
| Quant | Weights● | 4K◐ | 8K◐ | 16K◐ | 32K◐ | 64K◐ | 128K◐ |
|---|---|---|---|---|---|---|---|
| F16 | 12.85 GiB | 13.8 | 13.8 | 13.8 | 14.0 | 14.2 | 14.6 |
| Q8_0 | 11.28 GiB | 12.2 | 12.2 | 12.3 | 12.4 | 12.6 | 13.0 |
| MXFP4 | 11.28 GiB | 12.2 | 12.2 | 12.3 | 12.4 | 12.6 | 13.0 |
| Q6_K | 11.21 GiB | 12.1 | 12.2 | 12.2 | 12.3 | 12.5 | 13.0 |
| Q2_K_L | 10.95 GiB | 11.9 | 11.9 | 11.9 | 12.1 | 12.3 | 12.7 |
| Q5_K_M | 10.91 GiB | 11.8 | 11.9 | 11.9 | 12.0 | 12.2 | 12.7 |
| Q5_K_S | 10.91 GiB | 11.8 | 11.9 | 11.9 | 12.0 | 12.2 | 12.6 |
| Q4_K_M | 10.83 GiB | 11.7 | 11.8 | 11.8 | 11.9 | 12.1 | 12.6 |
| Q4_K_S | 10.82 GiB | 11.7 | 11.8 | 11.8 | 11.9 | 12.1 | 12.6 |
| Q4_1 | 10.78 GiB | 11.7 | 11.7 | 11.8 | 11.9 | 12.1 | 12.5 |
| Q3_K_M | 10.72 GiB | 11.6 | 11.7 | 11.7 | 11.8 | 12.0 | 12.5 |
| Q4_0 | 10.71 GiB | 11.6 | 11.7 | 11.7 | 11.8 | 12.0 | 12.4 |
| Q2_K | 10.68 GiB | 11.6 | 11.6 | 11.7 | 11.8 | 12.0 | 12.4 |
| Q3_K_S | 10.68 GiB | 11.6 | 11.6 | 11.7 | 11.8 | 12.0 | 12.4 |
Figures are GiB of total memory: weights plus KV cache plus compute buffer and backend overhead. Weights and KV are near-exact; the overhead term is modeled. Hover any cell for the breakdown.
Why other calculators disagree
A parameters × bits ÷ 8 estimate ignores two things that dominate at long context. First, the weights themselves are not the nominal rate — quantizations are mixtures, so the real file is consistently larger than the label implies. Second, most of this model's layers cache only a 128-token window rather than the full context.