Instinct MI250X
Instinct MI250X has 128 GB of VRAM at 3277 GB/s — about 119.04 GiB usable after driver and compositor overhead. 2085 of 2118 indexed models fit at 128K context with q8_0 KV.
What fits at 128K context
| Model | Best quant | Params | Weights● | KV● | Total in memory◐ | Headroom◐ | tok/s◐ |
|---|---|---|---|---|---|---|---|
| gpt-oss-120b-abliteratedMoE | I1-Q6_K | 117B | 115.67 GiB | 2.40 GiB | 118.96 GiB | 0.08 GiB | 84±37% |
| GLM-4.6VMoE | Q8_0 | 108B | 105.81 GiB | 12.22 GiB | 118.96 GiB | 0.08 GiB | 46±37% |
| Ornith-1.0-397BMoE | UD-IQ2_M | 397B | 115.83 GiB | 1.99 GiB | 118.77 GiB | 0.27 GiB | 94±37% |
| MiniMax-M2.7MoE | IQ3_M | 229B | 101.33 GiB | 16.47 GiB | 118.68 GiB | 0.36 GiB | 45±37% |
| Wizard-Vicuna-30B-Uncensored | I1-IQ3_M | 32.5B | 13.86 GiB | 103.59 GiB | 118.42 GiB | 0.62 GiB | 18±26.5% |
| archangel_sft-kto_llama30b | I1-IQ3_M | 32.5B | 13.86 GiB | 103.59 GiB | 118.42 GiB | 0.62 GiB | 18±26.5% |
| Qwen3-VL-235B-A22B-ThinkingMoE | Q3_K_M | 236B | 104.72 GiB | 12.48 GiB | 118.14 GiB | 0.90 GiB | 46±37% |
| Qwen3-VL-235B-A22B-InstructMoE | Q3_K_M | 236B | 104.72 GiB | 12.48 GiB | 118.14 GiB | 0.90 GiB | 46±37% |
| Qwen3-235B-A22BMoE | Q3_K_M | 235B | 104.72 GiB | 12.48 GiB | 118.14 GiB | 0.90 GiB | 46±37% |
| Qwen3-235B-A22B-abliteratedMoE | I1-Q3_K_M | 235B | 104.72 GiB | 12.48 GiB | 118.14 GiB | 0.90 GiB | 46±37% |
| Qwen3-235B-A22B-Thinking-2507MoE | Q3_K_M | 235B | 104.72 GiB | 12.48 GiB | 118.14 GiB | 0.90 GiB | 46±37% |
| Qwen3-235B-A22B-Instruct-2507MoE | Q3_K_M | 235B | 104.72 GiB | 12.48 GiB | 118.14 GiB | 0.90 GiB | 46±37% |
| MiniMax-M2.1MoE | Q3_K_L | 229B | 100.78 GiB | 16.47 GiB | 118.13 GiB | 0.91 GiB | 45±37% |
| MiniMax-M2MoE | Q3_K_L | 229B | 100.78 GiB | 16.47 GiB | 118.13 GiB | 0.91 GiB | 45±37% |
| Behemoth-X-123B-v2 | Q6_K | 123B | 93.68 GiB | 23.38 GiB | 118.11 GiB | 0.93 GiB | 18±26.5% |
| Mistral-Large-Instruct-2411 | Q6_K | 123B | 93.68 GiB | 23.38 GiB | 118.11 GiB | 0.93 GiB | 18±26.5% |
| WizardLM-Uncensored-SuperCOT-StoryTelling-30b | Q3_K_S | 32.5B | 13.10 GiB | 103.59 GiB | 117.66 GiB | 1.38 GiB | 18±26.5% |
| grok-2MoE | IQ3_XXS | 270B | 99.62 GiB | 17.00 GiB | 117.66 GiB | 1.38 GiB | 25±37% |
| Step-3.7-Flash | UD-IQ4_NL | 201B | 90.63 GiB | 26.05 GiB | 117.61 GiB | 1.43 GiB | 18±26.5% |
| GLM-4.6-REAP-268B-A32BMoE | Q2_K_L | 269B | 92.11 GiB | 24.44 GiB | 117.49 GiB | 1.55 GiB | 32±37% |
| MiniMax-M3MoE | IQ2_XXS | 427B | 108.60 GiB | 7.97 GiB | 117.49 GiB | 1.55 GiB | 62±37% |
| Trinity-Large-ThinkingMoE | IQ2_S | 399B | 112.03 GiB | 4.40 GiB | 117.36 GiB | 1.68 GiB | 83±37% |
| SuperHY3-abliterated-NVFP4MoE | IQ2_M | 172B | 95.10 GiB | 21.25 GiB | 117.29 GiB | 1.75 GiB | 37±37% |
| Hy3MoE | IQ2_M | 299B | 95.08 GiB | 21.25 GiB | 117.27 GiB | 1.77 GiB | 37±37% |
| dots.llm1.instMoE | IQ2_S | 143B | 50.40 GiB | 65.88 GiB | 117.20 GiB | 1.84 GiB | 17±37% |
| ERNIE-4.5-300B-A47B-PT | Q2_K_L | 300B | 101.76 GiB | 14.34 GiB | 117.13 GiB | 1.91 GiB | 18±26.5% |
| MiMo-V2.5MoEKV unresolved | UD-IQ3_S | 311B | 106.98 GiB | 7.97 GiB | 115.89 GiB | 3.15 GiB | 63±37% |
| GLM-4.7MoE | UD-IQ1_S | 358B | 90.50 GiB | 24.44 GiB | 115.88 GiB | 3.16 GiB | 34±37% |
| Hermes-4-405B | UD-IQ1_S | 406B | 81.23 GiB | 33.47 GiB | 115.88 GiB | 3.16 GiB | 18±26.5% |
| GLM-4.7-REAP-218B-A32BMoE | Q3_K_S | 218B | 90.39 GiB | 24.44 GiB | 115.76 GiB | 3.28 GiB | 31±37% |
| GLM-4.5MoE | UD-IQ1_S | 358B | 90.38 GiB | 24.44 GiB | 115.76 GiB | 3.28 GiB | 34±37% |
| Qwen3.5-397B-A17BMoE | UD-IQ1_M | 403B | 112.75 GiB | 1.99 GiB | 115.70 GiB | 3.34 GiB | 96±37% |
| GLM-4.6MoE | UD-IQ1_S | 357B | 90.28 GiB | 24.44 GiB | 115.66 GiB | 3.38 GiB | 34±37% |
| Gemma-4-Dark-Gemistry-31B | Q8_0 | 32.7B | 102.98 GiB | 11.25 GiB | 115.21 GiB | 3.83 GiB | 18±26.5% |
| Nex-N2-ProMoE | IQ2_S | 397B | 112.23 GiB | 1.99 GiB | 115.18 GiB | 3.86 GiB | 97±37% |
| gemma-2-27b-it | F32 | 27.2B | 101.43 GiB | 12.65 GiB | 115.12 GiB | 3.92 GiB | 18±26.5% |
| Qwen3-Coder-REAP-363B-A35BMoE | UD-IQ1_S | 363B | 97.24 GiB | 16.47 GiB | 114.64 GiB | 4.40 GiB | 40±37% |
| command-a-plus-05-2026-bf16MoE | IQ4_XS | 219B | 110.67 GiB | 2.35 GiB | 113.92 GiB | 5.12 GiB | 70±37% |
| Trinity-Large-TrueBaseMoE | I1-IQ2_S | 399B | 108.32 GiB | 4.40 GiB | 113.66 GiB | 5.38 GiB | 85±37% |
| MiMo-V2-FlashMoEKV unresolved | Q2_K_L | 310B | 104.70 GiB | 7.97 GiB | 113.62 GiB | 5.42 GiB | 64±37% |
| NVIDIA-Nemotron-3-Super-120B-A12B-BF16MoE | UD-Q6_K | 124B | 106.87 GiB | 5.84 GiB | 113.61 GiB | 5.43 GiB | 66±37% |
| command-r-35b-writer-v2 | I1-Q6_K | 35.0B | 26.74 GiB | 85.00 GiB | 112.74 GiB | 6.30 GiB | 19±26.5% |
| Llama-4-Maverick-17B-128E-InstructMoEKV unresolved | UD-TQ1_0 | 402B | 98.45 GiB | 12.75 GiB | 112.13 GiB | 6.91 GiB | 57±37% |
| step-3.5-flash | Q3_K_M | 199B | 84.04 GiB | 26.05 GiB | 111.01 GiB | 8.03 GiB | 19±26.5% |
| MiniMax-M2.5MoE | I1-IQ3_M | 229B | 93.13 GiB | 16.47 GiB | 110.48 GiB | 8.56 GiB | 46±37% |
| DeepSeek-Coder-V2-Instruct-0724MoE | Q3_K | 236B | 104.93 GiB | 4.48 GiB | 110.35 GiB | 8.69 GiB | 75±37% |
| DeepSeek-V2.5MoE | Q3_K | 236B | 104.93 GiB | 4.48 GiB | 110.35 GiB | 8.69 GiB | 75±37% |
| DeepSeek-Coder-V2-InstructMoE | Q3_K | 236B | 104.93 GiB | 4.48 GiB | 110.35 GiB | 8.69 GiB | 75±37% |
| DeepSeek-V4-FlashMoE | UD-IQ3_S | 291B | 109.25 GiB | 0.03 GiB | 110.24 GiB | 8.80 GiB | 113±37% |
| Mistral-Medium-3.5-128B | Q5_K_L | 128B | 85.78 GiB | 23.38 GiB | 110.21 GiB | 8.83 GiB | 19±26.5% |
| Qwen3.5-REAP-262B-A17BMoE | IQ3_M | 262B | 106.73 GiB | 1.99 GiB | 109.68 GiB | 9.36 GiB | 92±37% |
| MiniMax-M2.1-REAP-139B-A10BMoE | I1-Q5_K_M | 139B | 91.98 GiB | 16.47 GiB | 109.33 GiB | 9.71 GiB | 43±37% |
| m51Lab-MiniMax-M2.7-REAP-139B-A10BMoE | I1-Q5_K_M | 139B | 91.98 GiB | 16.47 GiB | 109.33 GiB | 9.71 GiB | 43±37% |
| MiniMax-M2.7-BF16-ultra-uncensored-hereticMoE | I1-IQ3_S | 229B | 91.94 GiB | 16.47 GiB | 109.29 GiB | 9.75 GiB | 46±37% |
| DeepSeek-V4-Flash-0731MoE | UD-IQ3_S | 304B | 108.10 GiB | 0.03 GiB | 109.08 GiB | 9.96 GiB | 114±37% |
| Mixtral-8x22B-Instruct-v0.1MoE | Q5_K_M | 141B | 93.11 GiB | 14.88 GiB | 108.94 GiB | 10.10 GiB | 28±37% |
| Mixtral-8x22B-v0.1MoE | Q5_K_M | 141B | 93.11 GiB | 14.88 GiB | 108.94 GiB | 10.10 GiB | 28±37% |
| Mixtral-8x22B-v0.1MoE | Q5_K_M | 141B | 93.10 GiB | 14.88 GiB | 108.94 GiB | 10.10 GiB | 28±37% |
| Qwen3.5-REAP-212B-A17BMoE | IQ4_XS | 212B | 105.39 GiB | 1.99 GiB | 108.34 GiB | 10.70 GiB | 88±37% |
| Trinity-Large-PreviewMoE | IQ2_S | 399B | 102.49 GiB | 4.40 GiB | 107.82 GiB | 11.22 GiB | 88±37% |
Speed is modeled, not measured: decode is memory-bandwidth bound, so tokens per second is bytes read per token against achievable bandwidth. Mixture-of-experts models carry a wider band because only the routed experts are read each step, and few have been measured publicly.
Measured on this card
| Workload◍ | Median | Middle 50% | Runs |
|---|---|---|---|
| Image generation | 11.55 it/s | 8.33–15.62 | 6 |
Aggregated from community-submitted runs, so the spread is wide by nature — it covers different models, resolutions, step counts and settings, not one controlled configuration. Read the middle 50% rather than the median alone. These figures are reproduced with attribution from vladmandic-sd-data-benchmark, which publishes no licence — so we display and link rather than redistribute them.
Questions people ask
- What AI models can a Instinct MI250X run?
- 2085 of 2118 indexed open-weight models fit a Instinct MI250X at 131,072 context with q8_0 KV cache, the largest being gpt-oss-120b-abliterated at I1-Q6_K. That covers text, vision-language, image, video and speech models.
- How much usable memory does a Instinct MI250X actually have?
- Its nameplate is 128 GB, but about 119.04 GiB is available to a model once driver and compositor overhead is accounted for.
- Is a Instinct MI250X fast for local AI?
- Its memory bandwidth is 3277 GB/s, and that figure — not teraflops — is what governs token generation speed. Capacity decides what you can run; bandwidth decides how fast it runs.