Instinct MI250X
Instinct MI250X has 128 GB of VRAM at 3277 GB/s — about 119.04 GiB usable after driver and compositor overhead. 2091 of 2118 indexed models fit at 32K context with f16 KV.
What fits at 32K context
| Model | Best quant | Params | Weights● | KV● | Total in memory◐ | Headroom◐ | tok/s◐ |
|---|---|---|---|---|---|---|---|
| grok-2MoE | Q3_K_S | 270B | 109.94 GiB | 8.00 GiB | 118.98 GiB | 0.06 GiB | 29±37% |
| MiniMax-M2.1MoE | I1-Q3_K_L | 229B | 110.22 GiB | 7.75 GiB | 118.86 GiB | 0.18 GiB | 63±37% |
| MiniMax-M2.5MoE | I1-Q3_K_L | 229B | 110.22 GiB | 7.75 GiB | 118.86 GiB | 0.18 GiB | 63±37% |
| MiniMax-M2.7-BF16-ultra-uncensored-hereticMoE | Q3_K_L | 229B | 110.22 GiB | 7.75 GiB | 118.86 GiB | 0.18 GiB | 63±37% |
| Qwen3.5-397B-A17BMoE | IQ2_XS | 403B | 116.79 GiB | 0.94 GiB | 118.68 GiB | 0.36 GiB | 102±37% |
| Solar-Open2-250BMoE | Q3_K_M | 250B | 111.63 GiB | 6.00 GiB | 118.56 GiB | 0.48 GiB | 71±37% |
| Qwen3.5-REAP-262B-A17BMoE | Q3_K_M | 262B | 116.42 GiB | 0.94 GiB | 118.31 GiB | 0.73 GiB | 93±37% |
| step-3.5-flash | IQ4_NL | 199B | 103.97 GiB | 13.03 GiB | 117.93 GiB | 1.11 GiB | 18±26.5% |
| MiMo-V2-FlashMoEKV unresolved | IQ3_XXS | 310B | 113.14 GiB | 3.75 GiB | 117.84 GiB | 1.20 GiB | 78±37% |
| gpt-oss-120b-abliteratedMoE | Q8_0 | 117B | 115.76 GiB | 1.15 GiB | 117.81 GiB | 1.23 GiB | 91±37% |
| Ornith-1.0-397BMoE | UD-IQ2_M | 397B | 115.83 GiB | 0.94 GiB | 117.72 GiB | 1.32 GiB | 103±37% |
| DeepSeek-Coder-V2-Instruct-0724MoE | Q3_K_L | 236B | 113.97 GiB | 2.11 GiB | 117.02 GiB | 2.02 GiB | 82±37% |
| DeepSeek-V2.5MoE | Q3_K_L | 236B | 113.97 GiB | 2.11 GiB | 117.02 GiB | 2.02 GiB | 82±37% |
| DeepSeek-Coder-V2-InstructMoE | Q3_K_L | 236B | 113.97 GiB | 2.11 GiB | 117.02 GiB | 2.02 GiB | 82±37% |
| Hermes-4-405B | IQ2_XXS | 406B | 99.91 GiB | 15.75 GiB | 116.84 GiB | 2.20 GiB | 18±26.5% |
| Hermes-3-Llama-3.1-405B | IQ2_XXS | 406B | 99.91 GiB | 15.75 GiB | 116.84 GiB | 2.20 GiB | 18±26.5% |
| Qwen3-Coder-REAP-363B-A35BMoE | UD-IQ1_M | 363B | 107.85 GiB | 7.75 GiB | 116.53 GiB | 2.51 GiB | 53±37% |
| dots.llm1.instMoE | Q4_1 | 143B | 84.24 GiB | 31.00 GiB | 116.16 GiB | 2.88 GiB | 29±37% |
| GLM-4.5-AirMoE | Q8_0 | 110B | 109.39 GiB | 5.75 GiB | 116.07 GiB | 2.97 GiB | 59±37% |
| GLM-4.5-Air-DerestrictedMoE | Q8_0 | 110B | 109.39 GiB | 5.75 GiB | 116.07 GiB | 2.97 GiB | 59±37% |
| Trinity-Large-ThinkingMoE | IQ2_S | 399B | 112.03 GiB | 2.67 GiB | 115.62 GiB | 3.42 GiB | 95±37% |
| Llama-3_1-Nemotron-51B-Instruct | Q5_K_L | 51.5B | 34.56 GiB | 80.00 GiB | 115.61 GiB | 3.43 GiB | 18±26.5% |
| Mixtral-8x22B-v0.1MoE | Q6_K | 141B | 107.60 GiB | 7.00 GiB | 115.56 GiB | 3.48 GiB | 30±37% |
| GLM-4.6-REAP-268B-A32BMoE | UD-IQ3_XXS | 269B | 102.71 GiB | 11.50 GiB | 115.15 GiB | 3.89 GiB | 47±37% |
| MiniMax-M2.1-REAP-139B-A10BMoE | I1-Q6_K | 139B | 106.40 GiB | 7.75 GiB | 115.04 GiB | 4.00 GiB | 58±37% |
| m51Lab-MiniMax-M2.7-REAP-139B-A10BMoE | Q6_K | 139B | 106.40 GiB | 7.75 GiB | 115.04 GiB | 4.00 GiB | 58±37% |
| Llama-3_3-Nemotron-Super-49B-v1_5 | Q5_K_L | 49.9B | 33.56 GiB | 80.00 GiB | 114.61 GiB | 4.43 GiB | 18±26.5% |
| Valkyrie-49B-v2.1 | Q5_K_L | 49.9B | 33.56 GiB | 80.00 GiB | 114.61 GiB | 4.43 GiB | 18±26.5% |
| Llama-3_3-Nemotron-Super-49B-v1 | Q5_K_L | 49.9B | 33.56 GiB | 80.00 GiB | 114.61 GiB | 4.43 GiB | 18±26.5% |
| Nex-N2-ProMoE | IQ2_S | 397B | 112.23 GiB | 0.94 GiB | 114.12 GiB | 4.92 GiB | 105±37% |
| Step-3.7-Flash | IQ4_XS | 201B | 99.94 GiB | 13.03 GiB | 113.89 GiB | 5.15 GiB | 18±26.5% |
| Llama-4-Scout-17B-16E-InstructMoEKV unresolved | Q8_0 | 109B | 106.67 GiB | 6.00 GiB | 113.59 GiB | 5.45 GiB | 59±37% |
| MiniMax-M3MoE | IQ2_XXS | 427B | 108.60 GiB | 3.75 GiB | 113.27 GiB | 5.77 GiB | 80±37% |
| Mistral-Medium-3.5-128B | Q6_K_L | 128B | 101.13 GiB | 11.00 GiB | 113.18 GiB | 5.86 GiB | 19±26.5% |
| command-a-plus-05-2026-bf16MoE | IQ4_XS | 219B | 110.67 GiB | 1.42 GiB | 112.99 GiB | 6.05 GiB | 74±37% |
| GLM-4.5MoE | UD-IQ1_M | 358B | 100.32 GiB | 11.50 GiB | 112.76 GiB | 6.28 GiB | 51±37% |
| GLM-4.7MoE | UD-IQ1_M | 358B | 100.27 GiB | 11.50 GiB | 112.71 GiB | 6.33 GiB | 51±37% |
| GLM-4.6VMoE | Q8_0 | 108B | 105.81 GiB | 5.75 GiB | 112.49 GiB | 6.55 GiB | 60±37% |
| GLM-4.6MoE | UD-IQ1_M | 357B | 100.02 GiB | 11.50 GiB | 112.46 GiB | 6.58 GiB | 51±37% |
| Hy3MoE | Q2_K | 299B | 101.28 GiB | 10.00 GiB | 112.22 GiB | 6.82 GiB | 56±37% |
| Trinity-Large-TrueBaseMoE | I1-IQ2_S | 399B | 108.32 GiB | 2.67 GiB | 111.92 GiB | 7.12 GiB | 97±37% |
| c4ai-command-r-plus-08-2024 | Q8_0 | 104B | 102.74 GiB | 8.00 GiB | 111.82 GiB | 7.22 GiB | 19±26.5% |
| MiniMax-M2.7MoE | UD-IQ4_NL | 229B | 103.15 GiB | 7.75 GiB | 111.78 GiB | 7.26 GiB | 65±37% |
| MiMo-V2.5MoEKV unresolved | UD-IQ3_S | 311B | 106.98 GiB | 3.75 GiB | 111.67 GiB | 7.37 GiB | 80±37% |
| Qwen3-VL-235B-A22B-ThinkingMoE | Q3_K_M | 236B | 104.72 GiB | 5.88 GiB | 111.53 GiB | 7.51 GiB | 60±37% |
| Qwen3-VL-235B-A22B-InstructMoE | Q3_K_M | 236B | 104.72 GiB | 5.88 GiB | 111.53 GiB | 7.51 GiB | 60±37% |
| Qwen3-235B-A22BMoE | Q3_K_M | 235B | 104.72 GiB | 5.88 GiB | 111.53 GiB | 7.51 GiB | 60±37% |
| Qwen3-235B-A22B-abliteratedMoE | I1-Q3_K_M | 235B | 104.72 GiB | 5.88 GiB | 111.53 GiB | 7.51 GiB | 60±37% |
| Qwen3-235B-A22B-Thinking-2507MoE | Q3_K_M | 235B | 104.72 GiB | 5.88 GiB | 111.53 GiB | 7.51 GiB | 60±37% |
| Qwen3-235B-A22B-Instruct-2507MoE | Q3_K_M | 235B | 104.72 GiB | 5.88 GiB | 111.53 GiB | 7.51 GiB | 60±37% |
| NVIDIA-Nemotron-3-Super-120B-A12B-BF16MoE | UD-Q6_K | 124B | 106.87 GiB | 2.75 GiB | 110.52 GiB | 8.52 GiB | 80±37% |
| MiniMax-M2MoE | Q3_K_M | 229B | 101.77 GiB | 7.75 GiB | 110.40 GiB | 8.64 GiB | 65±37% |
| DeepSeek-V4-FlashMoE | UD-IQ3_S | 291B | 109.25 GiB | 0.06 GiB | 110.26 GiB | 8.78 GiB | 112±37% |
| Gemma-4-Dark-Gemistry-31B | Q8_0 | 32.7B | 102.98 GiB | 6.17 GiB | 110.13 GiB | 8.91 GiB | 19±26.5% |
| GLM-4.7-REAP-218B-A32BMoE | Q3_K_M | 218B | 97.57 GiB | 11.50 GiB | 110.01 GiB | 9.03 GiB | 45±37% |
| ERNIE-4.5-300B-A47B-PT | Q2_K_L | 300B | 101.76 GiB | 6.75 GiB | 109.54 GiB | 9.50 GiB | 19±26.5% |
| DeepSeek-V4-Flash-0731MoE | UD-IQ3_S | 304B | 108.10 GiB | 0.06 GiB | 109.11 GiB | 9.93 GiB | 113±37% |
| gemma-2-27b-it | F32 | 27.2B | 101.43 GiB | 6.56 GiB | 109.03 GiB | 10.01 GiB | 19±26.5% |
| Devstral-2-123B-Instruct-2512 | Q6_K | 125B | 95.53 GiB | 11.00 GiB | 107.59 GiB | 11.45 GiB | 19±26.5% |
| GLM-4.6-Derestricted-v3MoE | IQ2_S | 357B | 94.86 GiB | 11.50 GiB | 107.30 GiB | 11.74 GiB | 52±37% |
Speed is modeled, not measured: decode is memory-bandwidth bound, so tokens per second is bytes read per token against achievable bandwidth. Mixture-of-experts models carry a wider band because only the routed experts are read each step, and few have been measured publicly.
Measured on this card
| Workload◍ | Median | Middle 50% | Runs |
|---|---|---|---|
| Image generation | 11.55 it/s | 8.33–15.62 | 6 |
Aggregated from community-submitted runs, so the spread is wide by nature — it covers different models, resolutions, step counts and settings, not one controlled configuration. Read the middle 50% rather than the median alone. These figures are reproduced with attribution from vladmandic-sd-data-benchmark, which publishes no licence — so we display and link rather than redistribute them.
Questions people ask
- What AI models can a Instinct MI250X run?
- 2091 of 2118 indexed open-weight models fit a Instinct MI250X at 32,768 context with f16 KV cache, the largest being grok-2 at Q3_K_S. That covers text, vision-language, image, video and speech models.
- How much usable memory does a Instinct MI250X actually have?
- Its nameplate is 128 GB, but about 119.04 GiB is available to a model once driver and compositor overhead is accounted for.
- Is a Instinct MI250X fast for local AI?
- Its memory bandwidth is 3277 GB/s, and that figure — not teraflops — is what governs token generation speed. Capacity decides what you can run; bandwidth decides how fast it runs.